Influence of reserpine and guanethidine on the responses of the isolated rat ileum to catecholamines.

نویسندگان

  • M R Khalighi
  • M A Haque
  • K Ziyai
  • F Firozian
  • H Parsaie
چکیده

The sensitivity of the isolated ileum of the rat to catecholamines has been investigated using normal, reserpinized and guanethidine treated animals. Both reserpine and guanethidine treatment produces supersensitivity to adrenaline, noradrenaline and to a greater extent to isoprenaline.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ANTISPASMODIC EFFECT OF AERIAL PART OF TEUCRIUM POLIUM L. ESSENTIAL OIL ON RAT ISOLATED ILEUM IN VITRO

Teucrium polium L. (Lamiaceae) is used in the traditional medicine of Iran for the treatment of disorders of the gastrointestinal tract. The essential oil from the aerial parts of T polium was assessed for antispasmodic activity and compared with the effect of atropine and dicyclomine. Acetylcholine and KC I were used for induction of contraction on rat isolated ileum. Teucrium polium essen...

متن کامل

بررسی اثر سیستم کانابینوییدی اندوژن بر عملکرد عصبی بافت کورپوس کاورنوزوم دستگاه تناسلی خارجی موشهای صحرایی نر

    Background & Aim: Although studies have shown the central effects of Endocannabinoid on erection, its' peripheral effect is unknown. The purpose of this study was to investigate the effect of the endogenous cannabinoid anandamide on the nonadrenergic noncholinergic(NANC) relaxant responses to electrical field stimulation in isolated rat corpus cavernosum, a crucial tissue in erectile functi...

متن کامل

Role of Histamine in Hypoxic Pulmonary Hypertension in the Rat

The present investigation was undertaken to see if any of the naturally occurring vasoactive substances was likely to act as a mediator for the pulmonary vasoconstrictor response to acute alveolar hypoxia. Rats were treated with agents that deplete local stores of vasoactive amines or inhibit their synthesis. Lungs from these animals were isolated, ventilated, and perfused with homologous blood...

متن کامل

Spasmolytic effect of Anethum graveolens (dill) fruit extract on rat ileum

Introduction: Dill (Anethum graveolens), a herb from from Umbelliferae, is used traditionally to treat convulsion and increasing milk production. Its antimicrobial, antihyperlipidaemic, anti-hypercholesteroaemic effects and gastric acid secretion reducing effect have been reported. The spasmolytic effect of dill fruit on rat uterus has also been shown recently. The aim of present study was to i...

متن کامل

Effect of Hydroalcoholic Extract of Pycnocycla spinosa on Rat Isolated Bladder Contraction

Hydroalcoholic extract of Pycnocycla spinosa is a relaxant of rat ileum and inhibits diarrhea in mice. As P. spinosa extract has spasmolytic activity on ileum, it could also affect other smooth muscles like bladder. Therefore, the aim of this study was to determine the effect of P. spinosa extract on rat bladder contraction. In an in vitro study, the effects of P. spinosa extract, nifedipine ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Indian journal of physiology and pharmacology

دوره 30 2  شماره 

صفحات  -

تاریخ انتشار 1986